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Nicoletta Gatti

PhD Student
PhD in Chemical Sciences - XLI cycle
Tutor: Alessandro GIUFFRIDA
  • 2025-Present: PhD Student in Chemical Sciences (XLI cycle), University of Catania
  • 2024 – 2025: Coordinated and continuous collaboration relationship for targeted scientific research with Epitech Group SpA 
  • 2025 – Current: Registration in the interprovincial register of Chemists and Physicists of Catania and Ragusa, section A
  • 2021 – 2023: Master’s degree in chemical sciences (LM-54) - Curriculum "Industry, Environment and Cultural Heritage" Thesis: "Realization of acrylic-based polymeric hydrogels adsorbents for the sequestration of emerging pollutants" obtained on 17/11/2023 with a grade of 110/110 laude, University of Catania
  • 2023: Internship for thesis activities at the Institute for Composite Polymers and Biomaterials (IPCB) National Research Council (CNR) in Catania  
  • 2017 – 2021: Bachelor’s degree in chemical science and technology (L-27) – Thesis: "Extraction of phenolic compounds from walnut shells: optimization and evaluation of antioxidant activity" obtained on 23/07/2021 with grade 110/110 laude, University of Catania

(last update: 28/11/2025)

Thesis title:  Designing hydrogels for controlled release of antibiotics and monitoring of chronic wounds: a patch against antibiotic resistance

The project proposes the development of an innovative hydrogel-based therapeutic platform for the advanced treatment of chronic wounds. The architecture of the system uses chemically modified hyaluronic acid to incorporate the chosen antibiotic, thus obtaining a controlled pharmacological release within the therapeutic window effective in counteracting the phenomenon of antibiotic resistance. The integration of biosensors with real-time monitoring capabilities makes it possible to obtain a dynamic diagnostic-therapeutic system, which provides crucial information on the status of the infection and the healing process, opening up new perspectives for personalized medicine.

Keywords: Antibiotic resistance, Mass spectrometry, Hyaluronic acid, Real-time biosensors

Gatti, N., Greco, V., Cuzzocrea, S., Crupi, R., Gugliandolo, E., & Giuffrida, A. (2025). Time-Controlled Online SPE: Strategic Approach for N-acylethanolamines Quantification in Complex MatricesJournal of Chromatography A, 466449. DOI: 10.1016/j.chroma.2025.466449