Cosimo Gianluca FORTUNA

Associate Professor of [CHIM/06]
Office: Cittadella Universitaria, V.le A. Doria 6, 95125 Catania. Edificio 1 corpo A piano 2 Stanza 2 (A2/2)
Phone: +39 095 738 5037
Fax: 095580138
Cosimo Fortuna

Associate Professor of Organic Chemistry (CHIM/06)

Courses: Organic Chemistry II at the B.D. course in Industrial Chemistry, Organic Chemistry I at the B.D. course in Scienze e Tecnologie Alimentari. 

Main research topics:

Prof. Cosimo Gianluca Fortuna was born in Catania on 22nd  January 1975; he got the degree in Chemistry in 2000 at Catania University. In 2004 he finished his Ph.D. During these three years he acquired a lot of experience in synthesis of heterocyclic chemistry as demonstrated by the financial support that the University of Catania assigned him to got his research. He took part in many school to improve his experience. He had a research contract (September/December 2000) with Chemistry Department, University of Catania. Since April 2004 to October 2006 he had a post-doctoral position at the Department of Chemistry, University of Catania. Since November 2006 he is an Organic Chemistry Assistant at the same Department.  He is member of Società Chimica Italiana and of the QSAR Society. From 2006 to 2009 he was a member and from December 2018 he is a member of the directive committee of the Società Chimica Italiana (SCI) young group. From 2009 to 2014 he is member of the directive committee of the Sicilian section of the SCI. He took part in organize committee of many national and international meetings.

He is  referee for four national journals.

He is member of the editorial board for the American Journal of Organic Chemistry.

Research projects:

•In 2002 he received financial support from the University of Catania (Funds for young researcher) as coordinator of a research project on: “Progettazione e sintesi di nuovi eterocicli ad attività antitumorale”.

•He was member of the Catania group (coordinated by Prof. G. Musumarra) of three national research project (Cofin 2002 and Cofin 2004 and 60%).

•Since 2010 to now he is COORDINATOR of a FIRB project entitled: “HETEROCYCLIC SYSTEMS IN THE MOLECULAR DESIGN OF POTENTIAL ANTIBACTERIAL COMPOUNDS”awarded a 189.000 euro research grants.

•From 2011 to 2013 he was member of the Catania group of a national research project. (Prin 09)

•  Since 2012 he is member of Bari group of a national research project. (Prin 12)

•  In 2012 he won  ISCRA-CINECA announcement (Italian SuperComputing Resource Allocation) with an Assigned budget of 40.000 hours.

Teaching activity:

From 2007 to 2009 he taught “Elementi di Chimica organica e laboratorio”

From 2006 to 2009 he taught “Chimica Organica per i beni culturali e protettivi consolidanti organici”

From 2008 to 2010 he taught “Degradazione di materiali organici nei Beni Culturali”

From 2009 to 2010 he taught Organic chemistry course 1.

From 2010 to 2011 he taught Organic chemistry course 2.

From 2012 he teaches Organic chemistry to " Scienze e Tecnologie alimentari"

He acquired a broad experience in synthetic organic chemistry, with special emphasis to heterocyclic compounds and in computational chemistry. He became, nationally, one of the most specialized researcher in heterocyclic synthesis. This is attested by many oral and poster presentations at national and international meetings. He is author of 54 refereed publications on international journals in the field of organic chemistry,  photochemistry, and computational chemistry. According to the ISI Web of Science and Scopus search engine he has an h-index of 17 and 720 citations. He had 42 papers in the last 10 years.

He is author of a national patent.

He was invited speaker in QSAR meeting CADD 2012 Chicago.

He done 10 oral communications and 50 posters at national and international meetings.

Cosimo Gianluca Fortuna publications in the last 5 years (ORCID ID: 0000-0003-1889-886x)


Ricci F, Carlotti B, Keller B, Bonaccorso C, Fortuna C, Goodson T, Elisei F, Spallettit A (2017). Enhancement of Two-Photon Absorption Parallels Intramolecular Charge-Transfer Efficiency in Quadrupolar versus Dipolar Cationic Chromophores. JOURNAL OF PHYSICAL CHEMISTRY. C, NANOMATERIALS AND INTERFACES, vol. 121, p. 3987-4001, ISSN: 1932-7447, doi: 10.1021/acs.jpcc.6b10629

Cesaretti A, Carlotti B, Elisei F, Fortuna C, Consiglio G, Spalletti A (2017). A cationic naphthyl derivative defies the non-equilibrated excited rotamers principle. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 19, p. 5262-5272, ISSN: 1463-9076, doi: 10.1039/c6cp08311k

Barresi V, Bonaccorso C, Cristaldi DA, Modica MN, Musso N, Pittalà V, Salerno L, Fortuna CG, (2017) Synthesis and experimental validation of new designed heterocyclic compounds with antiproliferative activity versus breast cancer cell lines MCF-7 and MDA-MB-231, Journal of Chemistry, vol. 17, doi: 10.1155/2017/9729284



Punzi A, Nicoletta F, Marzano G, Fortuna C, Dagar J, Brown TM, Farinola GM (2016). Synthetic Routes to TEG-Substituted Diketopyrrolopyrrole-Based Low Band-Gap Polymers. Eur. J. Org. Chem., p. 3233-3242, ISSN: 1434-193X, doi: 10.1002/ejoc.201600406

Paterno' A, D'Anna F, Fortuna C, Musumarra G (2016). Polarity study of ionic liquids with the solvatochromic dye Nile Red: a QSPR approach using in silico VolSurf plus descriptors. TETRAHEDRON, vol. 72, p. 3282-3287, ISSN: 0040-4020, doi: 10.1016/j.tet.2016.04.056

Carlotti B, Benassi E, Fortuna C, Barone V, Spalletti A, Elisei F (2016). Efficient Excited-State Symmetry Breaking in a Cationic Quadrupolar System Bearing Diphenylamino Donors. CHEMPHYSCHEM, vol. 17, p. 136-146, ISSN: 1439-4235, doi: 10.1002/cphc.201500784

Paterno A, Bocci G, Cruciani G, Fortuna C, Goracci L, Scire S, Musumarra G (2016). Cyto- and enzyme toxicities of ionic liquids modelled on the basis of VolSurf+ descriptors and their principal properties. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, vol. 27, p. 221-244, ISSN: 1062-936X, doi: 10.1080/1062936X.2016.1156571

Sgarlata C, Arena G, Fortuna C, Sciotto D, Bonaccorso C (2016). Cationic gemini guests promote the efficient self-assembly of capsular entities in water at neutral pH. SUPRAMOLECULAR CHEMISTRY, vol. 28, p. 544-550, ISSN: 1061-0278, doi: 10.1080/10610278.2015.1131986



Mazzoli Alessandra, Spalletti Anna, Carlotti Benedetta, Emiliani Carla, Fortuna C, Urbanelli Lorena, Tarpani Luigi, Germani Raimondo (2015). Spectroscopic Investigation of Interactions of New Potential Anticancer Drugs with DNA and Non-Ionic Micelles. JOURNAL OF PHYSICAL CHEMISTRY. B, vol. 119, p. 1483-1495, ISSN: 1520-6106, doi: 10.1021/jp510360u

Bonaccorso Carmela, De Rossi Francesca, Panigati Monica, Fortuna C, Forte Giuseppe, Brown Thomas M., Farinola Gianluca M., Musumarra Giuseppe (2015). Metal-free synthesis of bisthiophene-core donor acceptor organic photosensitizers for dye-sensitized solar cells. TETRAHEDRON, vol. 71, p. 7260-7266, ISSN: 0040-4020, doi: 10.1016/j.tet.2015.03.100

Perrone Maria Grazia, Vitale Paola, Panella Andrea, Fortuna C, Scilimati Antonio (2015). General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model. Eur. J. Med. Chem., vol. 94, p. 252-264, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2015.02.049

Carlotti B., Cesaretti A., Fortuna C, Spalletti A., Elisei F. (2015). Experimental evidence of dual emission in a negatively solvatochromic push-pull pyridinium derivative. Phys. Chem. Chem. Phys.,  vol. 17, p. 1877-1882, ISSN: 1463-9076, doi: 10.1039/c4cp04963b

Carlotti B., Benassi E., Cesaretti A., Fortuna C, Spalletti A., Barone V., Elisei F. (2015). An ultrafast spectroscopic and quantum mechanical investigation of multiple emissions in push-pull pyridinium derivatives bearing different electron donors. Phys. Chem. Chem. Phys., vol. 17, p. 20981-20989, ISSN: 1463-9076, doi: 10.1039/c5cp03207e

Consiglio Giuseppe, Failla Salvatore, Fortuna C, D'Urso Luisa, Forte Giuseppe (2015). Aggregation of a Zn(II)-salen complex: Theoretical study of structure and spectra. COMPUTATIONAL AND THEORETICAL CHEMISTRY, vol. 1067, p. 1-6, ISSN: 2210-271X, doi: 10.1016/j.comptc.2015.05.014

Benassi Enrico, Carlotti Benedetta, Fortuna C, Barone Vincenzo, Elisei Fausto, Spalletti Anna (2015). Acid-Base Strength and Acidochromism of Some Dimethylamino-Azinium Iodides. An Integrated Experimental and Theoretical Study. JOURNAL OF PHYSICAL CHEMISTRY. A, vol. 119, p. 323-333, ISSN: 1089-5639, doi: 10.1021/jp510982h



Barone Mariarita, Santagati Andrea, Graziano Adriana C. E., Fortuna C, Ronsisvalle Giuseppe, Cardile Venera (2014). Synthesis and Biological Evaluation of Sulfonilamidothienopyrimidinone Derivatives as Novel Anti-inflammatory Agents. MEDICINAL CHEMISTRY, vol. 10, p. 700-710, ISSN: 1573-4064

Carlotti Benedetta, Benassi Enrico, Spalletti Anna, Fortuna C, Elisei Fausto, Barone Vincenzo (2014). Photoinduced symmetry-breaking intramolecular charge transfer in a quadrupolar pyridinium derivative. Phys. Chem. Chem. Phys., vol. 16, p. 13984-13994, ISSN: 1463-9076, doi: 10.1039/c4cp00631c

Mazzoli Alessandra, Carlotti Benedetta, Consiglio Giuseppe, Fortuna C, Miolo Giorgia, Spalletti Anna (2014). Photobehaviour of methyl-pyridinium and quinolinium iodide derivatives, free and complexed with DNA. A case of bisintercalation. Photochem. Photobiol. Sci., vol. 13, p. 939-950, ISSN: 1474-905X, doi: 10.1039/c4pp00023d

Fortuna C, Berardozzi Roberto, Bonaccorso Carmela, Caltabiano Gianluigi, Di Bari Lorenzo, Goracci Laura, Guarcello Annalisa, Pace Andrea, Piccionello Antonio Palumbo, Pescitelli Gennaro, Pierro Paola, Lonati Elena, Bulbarelli Alessandra, Cocuzza Clementina E. A., Musumarra Giuseppe, Musumeci Rosario (2014). New potent antibacterials against Gram-positive multiresistant pathogens: Effects of side chain modification and chirality in linezolid-like 1,2,4-oxadiazoles. Bioorg. Med. Chem.,, vol. 22, p. 6814-6825, ISSN: 0968-0896, doi: 10.1016/j.bmc.2014.10.037

Carlotti Benedetta, Consiglio Giuseppe, Elisei Fausto, Fortuna C, Mazzucato Ugo, Spalletti Anna (2014). Intramolecular Charge Transfer of Push-Pull Pyridinium Salts in the Triplet Manifold. JOURNAL OF PHYSICAL CHEMISTRY. A, vol. 118, p. 7782-7787, ISSN: 1089-5639, doi: 10.1021/jp504963v

Carlotti Benedetta, Consiglio Giuseppe, Elisei Fausto, Fortuna C, Mazzucato Ugo, Spalletti Anna (2014). Intramolecular Charge Transfer of Push-Pull Pyridinium Salts in the Singlet Manifold. JOURNAL OF PHYSICAL CHEMISTRY. A, , vol. 118, p. 3580-3592, ISSN: 1089-5639, doi: 10.1021/jp407342q



Fortuna C. G.; Bonaccorso C.; Bulbarelli A.; Caltabiano G.; Rizzi L.; Goracci L.; Musumarra G.; Pace A.; Palumbo-Piccionello A.; Guarcello A.; Pierro P.; Cocuzza C. E.; Musumeci R.; “New Linezolid-like 1,2,4-oxadiazoles active against Gram-positive multiresistant pathogens.” Eur. J. Med. Chem., 65, 533-545, 2013.

Attanasio Francesco, Bonaccorso Carmela, Bellia Francesco, Cataldo Sebastiano, Fortuna C, Musumarra Giuseppe, Pignataro Bruno, Rizzarelli Enrico (2013). (E)-2-Cyano-3-(5 alpha-piperidin-1-yl-2,2 alpha-bithien-5-yl)acrylic Acid: A Fluorescent Probe for Detecting Prefibrillar Oligomers. Eur. J. Org. Chem. p. 3635-3639, ISSN: 1434-193X, doi: 10.1002/ejoc.201300241

Forte Giuseppe, Fortuna C, Salerno Loredana, Modica Maria N., Siracusa Maria A., Cardile Venera, Romeo Giuseppe, Bulbarelli Alessandra, Lonati Elena, Pittala Valeria (2013). Antitumor properties of substituted (alpha E)-alpha-(1H-indol-3-ylmethylene)benzeneacetic acids or amides. Bioorg. Med. Chem.,, vol. 21, p. 5233-5245, ISSN: 1464-3391, doi: 10.1016/j.bmc.2013.06.030

Cristaldi Domenico Andrea, Fortuna C, Gulino Antonino (2013). A photoelectron spectroscopy study of lava stones. ANALYTICAL METHODS, vol. 5, p. 3458-3462, ISSN: 1759-9660, doi: 10.1039/c3ay40136g

Cruciani, G, Baroni, M, Benedetti, P, Goracci, L, Fortuna C (2013). Exposition and reactivity optimization to predict sites of metabolism in chemicals. DRUG DISCOVERY TODAY, vol. 10, p. 155-165, ISSN: 1359-6446, doi: doi:10.1016/j.ddtec.2012.11.001

Barresi Vincenza, Bonaccorso Carmela, Consiglio Giuseppe, Goracci Laura, Musso Nicolo, Musumarra Giuseppe, Satriano Cristina, Fortuna C (2013). Modeling, design and synthesis of new heteroaryl ethylenes active against the MCF-7 breast cancer cell-line. MOLECULAR BIOSYSTEMS, vol. 9, p. 2426-2429, ISSN: 1742-206X, doi: 10.1039/c3mb70151d