ORGANIC CHEMISTRY III
Academic Year 2018/2019 - 3° Year
Teaching Staff: Giuseppe MUSUMARRA
Credit Value: 6
Scientific field: CHIM/06 - Organic chemistry
Taught classes: 35 hours
Exercise: 12 hours
Term / Semester: 1°
Credit Value: 6
Scientific field: CHIM/06 - Organic chemistry
Taught classes: 35 hours
Exercise: 12 hours
Term / Semester: 1°
Learning Objectives
Aim of this course is to provide a deeper insight into topics such as acid-base equilibria and heterocyclic chemistry whose knoledge is a prerequisite for understanding biological chemistry. Multivariate design is a general approach very useful in organic synthesis.
Course Structure
Lectures, seminars and exercises
Detailed Course Content
Acids and bases in organic chemistry: quantitative aspects. Heteroaromatics: reactivity with electrophiles and nucleophiles. Side chain reactivity of heterocycles and tautomerism of hydroxy and amino groups. Determination of tautomeric constants. Heterocycles in life and society: hereditary information, enzymes, vitamins, photosynthesis, pharmaceuticals and phytopharmaceuticals, dyes. Multivariate experimental design in organic synthesis.
Textbook Information
- J. B. Hendrickson, D. J. Cram e G. S. Hammond, Chimica Organica, Piccin capitolo 8.
- A.F. Pozharskii, A.T. Soldatenkov e A.R. Katritzky, Heterocycles in Life and Society, J. Wiley, New York, 1997.
- R. Carlson e J. E. Carlson, Design and Optimization in Organic Synthesis, Elsevier, 2005.