Organic Chemistry II and Laboratory A - L

Module Module 2

Acquire experience on the methodologies and techniques of organic synthesis through the preparation of some products and their structural determination.

Regarding the Dublin Descriptors, this course aims to transfer the following transversal competences to the student:
Knowledge and understanding:
 Inductive and deductive reasoning skills;
 Ability to rationalize and predict the reactivity of organic molecules;
 Ability to distinguish the difference between laboratory instruments;
 Ability to predict the glassware necessary for a specific reaction.

Ability to apply knowledge:
 Ability to design a synthetic path suitable for obtaining a precise organic molecule;
 Ability to assembly the glassware for a specific reaction;
 Ability to identify the conditions for optimal reactions for a synthetic strategy.

Autonomy of judgment:
 Critical reasoning skills;
 Self-assessment of learning through interactions in the classroom with colleagues and with the teacher.

Communication skills:
 Ability to describe in oral and written form, with properties of language and terminological rigor, one of the topics covered, making use of both power point presentations and the blackboard.

Lessons in classroom and in Laboratory

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Learning assessment may also be carried out on line, should the conditions require it.

Compulsory, with the exceptions established by the teaching regulations of the CdS. It is necessary to exceed 70% of the scheduled hours to be able to take the exam. In the event that this minimum number of hours is not reached, the student must pass a practical test before taking the ordinary exam.

If the teaching is given in a mixed or remote mode, the necessary changes with respect to what was previously stated may be introduced, in order to comply with the program envisaged and reported in the syllabus.

Intrumental techniques: NMR, UV-Vis, GC, GC-MS and HPLC

Reactions of 

• Aromatic nucleophilic substitution: synthesis of p-nitro aniline 

• Multi-step synthesis: benzocaine

• Synthesis of dibenzalacetone

1. D.L. Pavia, G.M. Lampman, G.S. Kritz, Introduction to Organic Laboratory, Saunder College Pubblishing.

2. R.M. Silverstein, F.X. Webster, Identificazione Spettroscopica di Composti Organici, Ambrosiana.

The exam, integrated with module 1, is aimed at ascertaining the acquisition of the basic concepts of the course and the ability to connect them with each other and with the experiments carried out in the laboratory, the ability to clearly explain the concepts using properly using the language scientific, the ability to use and quantitatively interpret experimental data by applying the concepts and methodologies acquired during the course.

The oral exam will focus both on the discussion of a laboratory experience and on topics from the theoretical course.

For each laboratory experience, the student must submit a detailed report within 7 days of the exam date, which is also subject to evaluation during the exam.

Verification of learning can also be carried out electronically, should the conditions require it.

column chromatographic separation

synthesis conditions

separation and purification of the desired compounds

spectroscopic characterization of organic compounds