ADVANCED BIOCHEMISTRY

Academic Year 2022/2023 - Teacher: VINCENZO GIUSEPPE NICOLETTI

Expected Learning Outcomes

The course of Advanced Biochemistry provides students with deep knowledge of those bichemical processes particularly interesting concerning variuos physio-pathological aspects.

Knowledge and understanding: students acquire in-depth knowledge of the most important aspects of biochemical processes whose understanding is evaluated during the lessons.

Applied knowledge and understanding: students will acquire the ability to apply what they have learned during the lectures.

Autonomy of judgment: students learn to interpret autonomously and objectively what they have learned during lessons and exercises.

Communication skills: students acquire communication skills thanks to the debates that arise during the lessons or to mini-seminars on specific topics of study.

Learning Skills: Learning skills are evaluated during lessons and exercises and through the oral exam.

Course Structure

class lessons and laboratory experiences​

In the eventuality of on-line lessons (due to COVID-19 pandemic), there could be necessary to adopt specific variations in order to guarantee the scheduled program.

Attendance of Lessons

Lessons attendance is mandatory.

Detailed Course Content

The principal topics concern:

  1. Mitochondrial respiratory chain and energy managing.
  2. Photosynthesis and energy managing
  3. Nutritional Biochemistry: caloric intake and natrium balance.
  4. Metabolic changes: nutrition-fast cycle.
  5. Glicemy control: metabolic correlations.
  6. Advanced glycation end products: production and effects.
  7. Plasmatic lipoproteins  (dislipidemy).
  8. Special aminoacids metabolism (metionin, folic acid, cystein, arginine).
  9. Mechanisms of hormones activity and growth factors.
  10. Molecular basis of angiogenesis in tumors and neurodegenerative diseases.
  11. Metabolism of bacteria.
  12. Elements of Neurochimistry.

Textbook Information

1) Nelson Cox. I principi di Biochimica di Lehninger. Zanichelli.

2) D. Voet, J.G. Voet, C.W. Pratt, Fondamenti di biochimica. Zanichelli.

3) R.K. Murray, D.K. Granner, P.A. Mayes, V.W. Rodwell. Harper's Biochimica illustrata – ed. Mc Graw-Hill. 

4) Bibliographic materials.

Course Planning

 SubjectsText References
1Una preparazione sufficiente sugli argomenti trattati e proposti durante la prova d'esame.Tutti i capitoli e/o i paragrafi dei testi di riferimento e del materiale fornito, congrui con gli argomenti trattati.

Learning Assessment

Learning Assessment Procedures

Written and/or oral exams about the issues treated during lessons.​

In the eventuality of COVID-19 pandemic restrictions, oral exams could be also performed on-line

Examples of frequently asked questions and / or exercises

Students will be invited for a revision of their written works. There are no frequently asked questions.